The ameliorative effects of virgin olive oil and olive leaf extract on amikacin-induced nephrotoxicity in the rat
نویسندگان
چکیده
منابع مشابه
The ameliorative effects of virgin olive oil and olive leaf extract on amikacin-induced nephrotoxicity in the rat
Amikacin is an important antibiotic, and its use is limited because of the induced nephrotoxicity. Thus, search for natural and synthetic agents that can moderate amikacin toxicity never stopped. The present study aims to investigate the possible ameliorative effects of virgin olive oil and olive leaf extract against the amikacin-induced nephrotoxicity in rat. METHODS 48 rats were distributed...
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متن کاملVirgin olive oil ameliorates deltamethrin-induced nephrotoxicity in mice: A biochemical and immunohistochemical assessment
OBJECTIVE A major class of synthetic pyrethroid insecticide, deltamethrin (DM), can elicit pathophysiological effects through oxidative stress in non-targeted organisms such as mammals. There is accumulating evidence that virgin olive oil (VOO), a rich source of polyphenolic components, have anti-oxidant, anti-inflammatory, and anti-apoptotic properties. This study aimed to determine the protec...
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ژورنال
عنوان ژورنال: Toxicology Reports
سال: 2015
ISSN: 2214-7500
DOI: 10.1016/j.toxrep.2015.09.007